Research project

Prof S. Khakoo: Peptide antagonism and NK cell activation: mechanism and relevance

Lead researchers:

Professor Salim Khakoo
Research funder:

Medical Research Council
Status:

Not active

Staff

Lead researchers

Professor Salim Khakoo

Professor of Hepatology

Connect with Salim

Email: S.I.Khakoo@soton.ac.uk

Research outputs

Activating killer cell immunoglobulin‐like receptors

Matthew D. Blunt & Salim I. Khakoo, 2020, International Journal of Immunogenetics, 47(1)

DOI: 10.1111/iji.12461

Type: article

Fine-mapping of genetic loci driving spontaneous clearance of hepatitis C virus infection

Hailiang Huang, Priya Duggal, Chloe L. Thio, Rachel Latanich, James J. Goedert, Alessandra Mangia, Andrea L. Cox, Gregory D. Kirk, Shruti Mehta, Jasneet Aneja, Laurent Alric, Sharyne M. Donfield, Matthew E. Cramp, Salim Khakoo, Leslie H. Tobler, Michael Busch, Graeme J. Alexander, Hugo R. Rosen, Brian R. Edlin, Florencia P. Segal, Georg M. Lauer, David L. Thomas, Mark J. Daly, Raymond T. Chung & Arthur Y. Kim, 2017, Scientific Reports, 7, 1-9

DOI: 10.1038/s41598-017-16011-2

Type: article

IL-12 and IL-15 induce the expression of CXCR6 and CD49a on peripheral natural killer cells

Theresa Hydes, Angela Noll, Gabriela Salinas-Riester, Mohammed Abuhilal, Thomas Armstrong, Zaed Hamady, John Primrose, Arjun Takhar, Lutz Walter & Salim I. Khakoo, 2017, Immunity, Inflammation and Disease, 6(1), 34-46

DOI: 10.1002/iid3.190

Type: article

KIR2DS2 recognizes conserved peptides derived from viral helicases in the context of HLA-C

Mohammed M. Naiyer, Sorcha A. Cassidy, Andrea Magri, Vanessa Cowton, Kevin Chen, Salah Mansour, Hariklia Kranidioti, Berenice Mbiribindi , Pauline Rettman, Scott Harris, Liam J. Fanning, Arend Mulder, Franz H.J. Claas, Andrew D. Davidson, Arvind H. Patel, Marco A. Purbhoo & Salim I. Khakoo, 2017, Science immunology, 2(15)

DOI: 10.1126/sciimmunol.aal5296

Type: article

HLA-Bw4 80(T) and multiple HLA-Bw4 copies combined with KIR3DL1 associate with spontaneous clearance of HCV infection in people who inject drugs

Christine Thöns, Tina Senff, Theresa J. Hydes, Angela R. Manser, Falko M. Heinemann, Andreas Heinold, Martin Heilmann, Arthur Y. Kim, Markus Uhrberg, Norbert Scherbaum, Georg M. Lauer, Salim I. Khakoo & Jörg Timm, 2017, Journal of Hepatology, 67(3), 462-470

DOI: 10.1016/j.jhep.2017.03.040

Type: article