Point Of Care Blood Cell Analysis

Project overview

The project will develop a new micro-technology for label-free point of care (PoC) cell analysis, paying particular attention to accurate determination of low abundance cell populations for a five-part differential for full blood count (FBC). The FBC is the single most common clinical measurement used to provide information on a patient's health in almost every single disease, indicating the large commercial impact of the work proposed here. The project will also develop new low pressure, low power microfluidics, minimally invasive sample extraction and low-volume processing and new integrated electronics. We will also develop methods for meaningful information delivery to patient and doctor. The end-results will be solutions and know-how for implementation of a handheld PoC Full Blood Count (FBC) system, based on high speed single cell impedance spectroscopy in a microfluidic format. This project will provide breakthroughs in functionality, minaturisation and consumer acceptability to realise a true PoC FBC.

Staff

Lead researchers

Professor Hywel Morgan MBE

Professor of Bioelectronics

Research interests

Microfluidics
Bio-sensors
Lab-on-a-chip technologies

Connect with Hywel

Email: hm@ecs.soton.ac.uk

Other researchers

Emeritus Professor Donna Davies

Research interests

Mechanisms of lung diseases
Viral-induced exacerbations of lung disease
Asthma

Connect with Donna

Email: D.E.Davies@soton.ac.uk

Professor Judith Holloway BSc (Hons), PhD, PGCert, PFHEA, NTF

Research interests

HACASE: A simple effective educational model for session design: Prof Holloway has designed a…
MSc Allergy education: Prof Holloway's team explore innovations and the effectiveness of teac…
Allergy bitesize education (short e-courses for CPD): Prof Holloway has led the development o…

Connect with Judith

Email: J.Holloway@soton.ac.uk