Research project

Phil Gale - Synthetic Anionophores with Therapeutic Potential - EP/J009687/1

Research funder:

EPSRC
Status:

Not active

Research outputs

Anion carriers as potential treatments for cystic fibrosis: transport in cystic fibrosis cells, and additivity to channel-targeting drugs

2019, Chemical Science, 2019(10), 9663-9672

DOI: 10.1039/C9SC04242C

Type: article

Investigating the influence of steric hindrance on selective anion transport

2019, Molecules, 24(7), 1-10

DOI: 10.3390/molecules24071278

Type: article

Fluorinated synthetic anion carriers: experimental and computational insights into transmembrane chloride transport

Michael Spooner, Hongyu Li, Igor Marques, Pedro M.R. Costa, Xin Wu, Ethan NW Howe, Nathalie Busschaert, Stephen Moore, Mark Light, David N. Sheppard, Vítor Félix & Philip Gale, 2018, Chemical Science

DOI: 10.1039/C8SC05155K

Type: article

Full elucidation of the transmembrane anion transport mechanism of squaramides using

2018, Physical Chemistry Chemical Physics, 20(32), 20796-20811

DOI: 10.1039/c8cp02576b

Type: article

A synthetic ion transporter that disrupts autophagy and induces apoptosis by perturbing cellular chloride concentrations

2017, Nature Chemistry, 9, 667–675

DOI: 10.1038/nchem.2706

Type: article