Research project

Crystal Drops

Project overview

Droplet microfluidics for compartmentalised nanocrystal preparation

Lead researchers

Associate Professor

Time-Resolved Structural Biology The emergence of serial crystallography brings many exciting possibilities for structural biology but also brings the challenge of preparing many thousands of sub-micron crystals. To address this, we are working with Ivo Tews and Allen Orville to develop high throughput droplet microfluidic systems. Here volumetric confinement of the phase diagram defines growth limits for producing monodisperse protein crystals. Beyond this, the microfluidic processors can be interfaced with the beam line to enable dynamic structural biology.

Connect with Jonathan

Email: J.J.West@soton.ac.uk