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Research project

Microfluidic Platelet Profiling: Linking Platelet Reactivity With Molecular Signatures For Thrombosis Risk Prediction

Staff

Lead researchers

Dr Jonathan West

Associate Professor

Research interests

  • Time-Resolved Structural Biology The emergence of serial crystallography brings many exciting possibilities for structural biology but also brings the challenge of preparing many thousands of sub-micron crystals. To address this, we are working with Ivo Tews and Allen Orville to develop high throughput droplet microfluidic systems. Here volumetric confinement of the phase diagram defines growth limits for producing monodisperse protein crystals. Beyond this, the microfluidic processors can be interfaced with the beam line to enable dynamic structural biology.
Connect with Jonathan

Email: J.J.West@soton.ac.uk

Other researchers

Professor Nicola Englyst

Professorial Fellow-Education

Research interests

  • Educational projects
  • Patient-centred language in social media
  • Lab based research (collaborative) on platelets and microvesicles
Connect with Nicola

Email: N.A.Englyst@soton.ac.uk

Dr Jane Gibson

Associate Professor
Connect with Jane

Email: J.Gibson@soton.ac.uk

Professor Diana Baralle B.Sc., M.B.B.S, M.D, FRCP

Professor of Genomic Medicine

Research interests

  • RNA
  • Splicing
  • Genomics
Connect with Diana

Email: D.Baralle@soton.ac.uk

Research outputs