Research project

D Boche: High throughput and high resolution digital slide scanner Nanozoomer

Lead researchers:

Professor Delphine Boche
Research funder:

Alzheimers Research UK
Status:

Not active

Staff

Lead researchers

Professor Delphine Boche

Professor of Neuroimmunopathology

Research interests

Neuroimmunology and neurodegeneration
Immunophenotyping immune cells
Human brain pathology

Connect with Delphine

Email: D.Boche@soton.ac.uk

Research outputs

Changes in the locus Coeruleus during the course of Alzheimer’s disease and their relationship to cortical pathology

Rebecca Claire Beardmore, Matthew Durkin, Faizan Zayee-Mellick, Laurie C. Lau, James A.R. Nicoll, Clive Holmes & Delphine Boche, 2024, Neuropathology and Applied Neurobiology

Type: article

The mitochondrial protein TSPO in Alzheimer’s disease: relation to the severity of AD pathology and the neuroinflammatory environment

Emma F. Garland, Oliver Dennet, Laurie Lau, David S. Chatelet, Michel Bottlaender, James A.R. Nicoll & Delphine Boche, 2023, Journal of Neuroinflammation, 20(1)

DOI: 10.1186/s12974-023-02869-9

Type: article

Immune environment of the brain in schizophrenia and during the psychotic episode: a human post-mortem study

Livia De Picker, Gerardo Mendez-Victoriano, Rhys Richards, Alexander Gorvett, Simeon Lyons, George Buckland, Tommaso Tofani, Jeanette Norman, David Chatelet, James Nicoll & Delphine Boche, 2021, Brain, Behavior and Immunity, 97, 319-327

DOI: 10.1016/j.bbi.2021.07.017

Type: review

Microglial motility in Alzheimer’s disease and after Aβ42 immunotherapy: a human post-mortem study

Diana, Karina Franco Bocanegra, Bethany George, Laurie C. Lau, Clive Holmes, James A.R. Nicoll & Delphine Boche, 2019, Acta Neuropathologica Communications, 7(1), 174

DOI: 10.1186/s40478-019-0828-x

Type: article

Persistent neuropathological effects 14 years following amyloid-β immunisation in Alzheimer’s disease

James A.R. Nicoll, George R. Buckland, Charlotte H. Harrison, Anton Page, Scott Harris, Seth Love, James W. Neal, Clive Holmes & Delphine Boche, 2019, Brain, 142(7), 2113-2126

DOI: 10.1093/brain/awz142

Type: article