Research project

B-cell receptor signalling in B-cell malignancies: Identifying strategies for optimal therapeutic intervention based on common and distinct responses

Lead researchers:

Emeritus Professor Graham Packham
Other researchers:

Professor Jon Strefford,

Professor Francesco Forconi,

Professor Mark Cragg
Research funder:

Cancer Research UK
Status:

Not active

Staff

Lead researchers

Emeritus Professor Graham Packham

Connect with Graham

Email: G.K.Packham@soton.ac.uk

Other researchers

Professor Jon Strefford PhD

Head of School

Connect with Jon

Email: jcs@soton.ac.uk

Professor Francesco Forconi

Professor of Haematology

Connect with Francesco

Email: F.Forconi@soton.ac.uk

Professor Mark Cragg

Professor in Experimental Cancer Biology

Research interests

Antibody biology
Antibody engineering
Cancer Immunotherapy

Connect with Mark

Email: M.S.Cragg@soton.ac.uk

Research outputs

Exploring 2-sulfonylpyrimidine warheads as acrylamide surrogates for targeted covalent inhibition: a BTK story

Ruxandra Moraru, Beatriz Valle-Argos, Annabel Minton, Lara Buermann, Suyin Pan, Thomas E. Wales, Raji E. Joseph, Amy H. Andreotti, Jonathan C. Strefford, Graham Packham & Matthias G.J. Baud, 2024, Journal of Medicinal Chemistry, 67(16), 13572-13593

DOI: 10.1021/acs.jmedchem.3c01927

Type: article