Research group

Microfluidics and Sensors

Two fingers wearing globes holding a microchip

Microfluidics is the interdisciplinary study of the behaviour, manipulation and application of fluid at the microscale. It underpins the concept of the lab-on-a-chip, where multiple key components and operations are integrated onto one small platform.

About

 

This is an important underlying technology with applications across a diverse range of fields including medicine, chemistry and oceanic research. 

Scientists across the Institute of Life Sciences have been driving microfluidics research and application forward for more than two decades. With a translational approach many of our fundamental science discoveries have resulted in novel micro-engineered devices which have paved the way for how patients are treated in hospital.  

Our research teams span fields from engineering and physics to medicine and biology and are carrying out research into areas such as single cell analysis, organ-on-a-chip, neuroscience, clinical diagnostics, personalised medicine and environmental monitoring. Our scientists use microfluidic devices and systems to find solutions to some of today’s biggest challenges including antimicrobial resistance and ocean climate changes. 

As well as using microfluidics to provide engineering solutions for biological and healthcare applications our scientists are also training the next generation of microfluidics experts. Our postgraduate students work alongside international leaders in their field, shaping and developing research projects as well as conducting their own research investigations. 

Staff and students alike also have access to cutting-edge facilities which contain state of the art analytical equipment, dedicated cell and tissue culture laboratory and rapid prototyping clean rooms. 

People, projects and publications

People

Professor Raimund Ober

Prof of Imaging & Biomedical Engineering
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Dr Ralph Gordon BSc, MSc, PhD, FHEA

Postdoctoral Research Fellow

Research interests

  • Thermal and Exercise Physiology
  • Heat Acclimation/Acclimatization
  • Skin Cooling

Accepting applications from PhD students

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Professor Ratko Djukanovic

Professor of Medicine

Research interests

  • Professor Djukanovic has a lifelong interest in asthma, especially its severe forms. where his focus is on: 1) underlying pathobiological mechanisms of asthma, 2) stratification of asthma into clinical phenotypes and mechanism-based endotypes, 3) unmet needs of severe asthma management. He also has an interest in the mechanisms and treatments of severe viral infections of the lung.
  • Underlying mechanisms of asthma: Professor Djukanovic has conducted pioneer studies into the pathology of asthma, applying research bronchoscopy  (with endobronchial biopsy and bronchoalveolar lavage) and sputum induction. He led the initial task forces which defined the use of these two techniques, thereby paving the way for standardised research approches that enabled in-depth descriptions of the roles of various inflammatory cells and their mediators. He developed an explant model, consisting of bronchial biopsies placed into tissue culture, that could be stimulated ex vivo with relevant triggers, applying as needed, novel agents not yet approved for in vivo use in humans volunteers. 
  • Stratification of asthma into clinical phenotypes and mechanism-based endotypes: Professor Djukanovic led the discovery of biomarkers using omics technology (transcriptomics, proteomics, lipidomics, breathomics). After the first ever study of transcriptomics biomarkers in the epithelium of patients with Chronic Obstructive Pulmonary Disease (COPD), together with a colleague from Amsterdam and two colleagues from Imperial College, London, he created a large (€27 milllion) programme for severe asthma (U-BIOPRED), funded by the EU Innovative Medicines Initiative. This has resulted in more than 100 publications, providing insight into novel phenotypes and endotypes of asthma.
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Professor Rebecca Hoyle

Assoc Vice-President Interdisc Research

Research interests

  • Multimorbidity across the lifecourse
  • Cooperation in social networks and evolution of cooperation
  • Quantitative genetics of transgenerational effects

Accepting applications from PhD students

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Dr Reuben Pengelly PhD, SFHEA

Principal Teaching Fellow

Research interests

  • Student attitudes towards academic integrity
  • Splicing regulation of metal binding proteins

Accepting applications from PhD students

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Dr Richard Cook

Associate Professor

Research interests

  • Mechanical and tribological testing of hydrogels for orthopaedic and tissue engineering
  • The tribology of tooth brushing.
  • Efficacy testing of products for dental hypersensitivity management.
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Dr Richard Meek

Senior Research Fellow

Research interests

  • Eukaryotic Glycobiology
  • Carbohydrate-active Enzymes
  • Post-translational Modifications

Accepting applications from PhD students

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Professor Rob Ewing

Professor

Accepting applications from PhD students

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Professor Robert Read

Chair of Infectious Diseases
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Interdisciplinary research teams collaborate across engineering technologies with applications in medicine, biology and environment to create novel and disruptive research activity in areas including diagnostics, infectious diseases and water testing.
Professor of Bioelectronics

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