Research centre

NIHR Southampton Clinical Research Facility

Outside of Southampton General Hospital, featuring a rainbow façade.

The NIHR Southampton Clinical Research Facility is an extensive, dedicated space for early-stage clinical research located at Southampton General Hospital.

Part of Medicine

About

The NIHR Southampton Clinical Research Facility (CRF) is delivered in a long-standing partnership between the University of Southampton and University Hospital Southampton NHS Foundation Trust. It is funded by the National Institute for Health and Care Research (NIHR). 

NIHR CRFs support the delivery of early-phase and complex studies in purpose-built facilities in NHS hospitals.

Forefront of research

The NIHR Southampton CRF provides a comfortable, safe environment for volunteers to take part in research. 

The CRF has completed over 800 clinical trials in the last 10 years. They range from studies testing new treatments, vaccines and medical devices in patients for the very first time (first-in-human trials) through to early safety and efficacy trials (Phase II and complex phase III trials). 

The 2,000m2 facility delivers research studies funded by the NIHR, the life sciences industry and other organisations. 

Studies cover a large range of diseases and conditions in both adults and children. These include many types of cancer, asthma, COPD, infection and inflammation, and musculoskeletal and neurological conditions. 

The facility is part of the UKCRF Network, which consists of around 54 Clinical Research Facilities across the UK and Ireland. The NIHR Southampton CRF works extremely closely with the NIHR Southampton Biomedical Research Centre and collaborates with other local NHS trusts and universities through CRN Wessex.

Visit the NIHR Southampton Clinical Research Facility website

People, projects and publications

People

Professor Gareth Griffiths

Director Clinical Trials Unit

Research interests

  • Gareth Griffiths is Professor of Clinical Trials and directs our Southampton Clinical Trials Unit.  He works with clinicians, research groups and other scientists in the development of important clinical trials and other well-designed studies that aim to improve the treatment of a range of cancers and other diseases, and early diagnosis of cancer.
  • His works spans the different phases of clinical trials, from small dose finding and safety studies involving a handful of patients to larger trials of hundreds of patients looking at whether the treatments are better than the current standard treatments.  His early diagnosis studies include thousands of patients looking at new ways to detect cancer early.  Ultimately, these studies could help change the way that patients are treated for the better, by creating the evidence so as the new treatments becomes the standard of care for future patients treated in the NHS.
  • Phase I-III clinical trials
Connect with Gareth