Research project

Dr H M Haitchi ADAM33 gene and environmental interactions in developing lungs and their involvement in the early life origin of asthma

Staff

Lead researchers

Professor Hans Michael Haitchi MD, MMed(INT), PhD, PD, MRCP(London), FHEA, PGcert

Professor

Research interests

  • Study of the asthma susceptibility gene A Disintegrin and Metalloprotease 33 (ADAM33) in early life and adult asthma and other chronic lung diseases.
  • Development of novel Anti-ADAM33 agents as potential disease modifying asthma therapy.
  • Multiomic study of the influence of the maternal environment (e.g. allergic asthma, obesity) during pregnancy on ADAM33 and other mediators and the early origin of lung disease in the Maternal Environment in Pregnancy (MEP) cohort.
Connect with Hans Michael

Research outputs

Julia Hoffmann, Leigh M. Marsh, Mario Pieper, Elvira Stacher, Bahil Ghanim, Gabor Kovacs, Peter König, Heinrike Wilkens, Hans Michael Haitchi, Gerald Hoefler, Walter Klepetko, Horst Olschewski, Andrea Olschewski & Grazyna Kwapiszewska, 2015, American Journal of Physiology: Lung Cellular and Molecular Physiology, 308(10), L1002-L1013
Type: article
Alexander W. Lange, Hans Michael Haitchi, Timothy D. LeCras, Anusha Sridharan, Yan Xu, Susan E. Wert, Jeanne James, Nicholas Udell, Philipp J. Thurner & Jeffrey A. Whitsett, 2014, Developmental Biology, 387(1), 109-120
Type: article
Gang Chen, Thomas R. Korfhagen, Christopher L. Karp, Soren Impey, Yan Xu, Scott H. Randell, Joseph Kitzmiller, Yutaka Maeda, Hans Michael Haitchi, Anusha Sridharan, Albert P. Senft & Jeffrey A. Whitsett, 2014, American Journal of Respiratory and Critical Care Medicine, 189(3), 301-313
Type: article
Philip N. Sanders, Olha M. Koval, Omar A. Jaffer, Anand M. Prasad, Thomas R. Businga, Jason A. Scott, Patrick J. Hayden, Elizabeth D. Luczak, David D. Dickey, Chantal Allamargot, Alicia K. Olivier, David K. Meyerholz, Alfred J. Robison, Danny G. Winder, Timothy S. Blackwell, Ryszard Dworski, David Sammut, Brett A. Wagner, Garry R. Buettner, Robert M. Pope, Francis J. Miller, Megan E. Dibbern, Hans Michael Haitchi, Peter J. Mohler, Peter H. Howarth, Joseph Zabner, Joel N. Kline, Isabella M. Grumbach & Mark E. Anderson, 2013, Science Translational Medicine, 5(195), 195ra97
Type: article