Research project

Core Capability for Chemistry Research in Southampton - Brown - EPSRC

Lead researchers:

Professor Richard Brown
Other researchers:

Professor Gill Reid
Research funder:

EPSRC
Status:

Not active

Staff

Lead researchers

Professor Richard Brown

Professor of Organic Chemistry

Research interests

Organic synthesis
Total synthesis of natural products
Asymmetric synthesis

Connect with Richard

Email: R.C.Brown@soton.ac.uk

Other researchers

Professor Gill Reid

PROFESSOR OF CHEMISTRY

Research interests

Synthetic inorganic chemistry
Design and synthesis of new macrocyclic and multidentate ligands involving donor atoms from G…
Coordination chemistry with s-, p-, d- and f-block metal ions

Connect with Gill

Email: G.Reid@soton.ac.uk

Research outputs

Exploring 2-sulfonylpyrimidine warheads as acrylamide surrogates for targeted covalent inhibition: a BTK story

Ruxandra Moraru, Beatriz Valle-Argos, Annabel Minton, Lara Buermann, Suyin Pan, Thomas E. Wales, Raji E. Joseph, Amy H. Andreotti, Jonathan C. Strefford, Graham Packham & Matthias G.J. Baud, 2024, Journal of Medicinal Chemistry, 67(16), 13572-13593

DOI: 10.1021/acs.jmedchem.3c01927

Type: article

Conformational analysis of 1,3-difluorinated alkanes

William G. Poole, Florent Peron, Stephen J. Fox, Neil Wells, Chris Kriton Skylaris, Jonathan W. Essex, Ilya Kuprov & Bruno Linclau, 2024, Journal of Organic Chemistry, 89(12), 8789–8803

DOI: 10.1021/acs.joc.4c00670

Type: article

Quantitative analysis of 2D EXSY NMR spectra of strongly coupled spin systems in transmembrane exchange

Dmitry Shishmarev, Clement Q. Fontenelle, Bruno Linclau, Ilya Kuprov & Philip W. Kuchel, 2023, ChemBioChem, e202300597

DOI: 10.1002/cbic.202300597

Type: article

Rapid investigation of the effect of binary and ternary solvent gradient mixtures on reaction outcomes using a continuous flow system

Dawid Drelinkiewicz, Tom J.A. Corrie & Richard J. Whitby, 2023, Reaction Chemistry and Engineering

DOI: 10.1039/d3re00464c

Type: article

Obtaining pure ¹H NMR spectra of individual pyranose and furanose anomers of reducing deoxyfluorinated sugars

Gabija Poškaitė, David E. Wheatley, Neil Wells, Bruno Linclau & Davy Sinnaeve, 2023, Journal of Organic Chemistry, 88(19), 13908-13925

DOI: 10.1021/acs.joc.3c01503

Type: article

Aryl-aryl cross-coupling reactions without reagents or catalysts: photocyclization of ortho-Iodoaryl ethers and related compounds via triplet aryl cation intermediates

David C. Harrowven, Wei Sun, Richard C.D. Brown & Luke Wilding-Steele, 2023, ChemComm, 59(72), 10797-10800

DOI: 10.1039/D3CC03271J

Type: article

Spatio-temporal detachment of homogeneous electron transfer in controlling selectivity in mediated organic electrosynthesis

Jack W. Hodgson, Ana A. Folgueiras Amador, Derek Pletcher, David C. Harrowven, Guy Denuault & Richard C.D. Brown, 2023, Faraday Discussions, 247, 302-323

DOI: 10.1039/D3FD00089C

Type: article