Research project

Dr Jane Cleal: Functional gene mapping of the endometrial phenotype involved in successful pregnancy: combining 3D imaging and single cell transcriptomics

Staff

Lead researchers

Dr Jane Cleal PhD

Associate Professor

Research interests

  • Areas of Scientific Expertise:
  • Reproductive Cell Biology – Fundamental mechanisms of cell biology in placenta and endometrium and the impact on the intra-uterine environment, fetal development and lifelong health.Regulation of Reproductive Cell Biology – Maternal exposures and molecular regulation of cellular gene expression, phenotype and function in placenta and endometrium and the clinical translation.Disease/phenotype – Fetal growth, Obesity, Cardiometabolic programming, Subfertility, Recurrent pregnancy loss.Cellular mechanisms – Membrane transport, endocytosis, vesicular transport & signalling, gene transcription, microRNA biology, epigenetic regulation.Vitamin D - Transport, regulation, metabolism and signalling.
Connect with Jane
Other researchers

Professor Rohan Lewis PhD, FTPS

Prof of Placental&Integrative Physiology
Connect with Rohan

Professor Ying Cheong

Professor of Reproductive Medicine
Connect with Ying

Research outputs

Jennifer E. Pearson-Farr, Regan Doherty, David S. Chatelet, Patricia Goggin, Ka Ying Bonnie Ng, Jane S. Lucas, Jane K. Cleal, Ying C. Cheong & Rohan M. Lewis, 2024, Reproduction, 167(1)
Type: article
Jennifer Pearson-Farr, Gabrielle Wheway, Maaike SA Jongen, Patricia Goggin, Rohan Lewis, Ying Cheong & Jane Cleal, 2022, Reproduction and Fertility, 3(3), 162-72
Type: article
Rebecca Davies, Catherine Griffiths, Kathryn Askelund, Eleni Palaiologou, Jane K. Cleal, Anton Page, David S. Chatelet, Patricia Goggin, Larry Chamley & Rohan M. Lewis, 2022, Placenta, 123, 24-30
Type: article
Brogan Ashley, Claire Simner, Antigoni Manousopoulou, Carl Jenkinson, Felicity Hey, Jennifer M. Frost, Faisal I Rezwan, Cory H White, Emma Lofthouse, Emily Hyde, Laura, Diana Frances Cooke, Sheila Barton, Pamela A Mahon, Elizabeth Curtis, Rebecca Moon, Sarah Crozier, Hazel Inskip, Keith Godfrey, John Holloway, Cyrus Cooper, Kerry S. Jones, Rohan Lewis, Martin Hewison, Spiros Garbis, Miguel R. Branco, Nicholas Harvey & Jane Cleal, 2022, eLife, 11
Type: article
Rohan M. Lewis & Jennifer E. Pearson-Farr, 2020, Placenta, 102, 55-60
Type: review