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Research project

B Linclau - IB Catalyst - BB/M028941/1

Staff

Other researchers

Dr Seung Lee

Associate Professor

Research interests

  • Chemical biology
  • Antimicrobial resistance
  • Glycan processing enzymes
Connect with Seung

Email: S.S.Lee@soton.ac.uk

Collaborating research institutes, centres and groups

Research outputs

Obtaining pure 1H NMR spectra of individual pyranose and furanose anomers of reducing deoxyfluorinated sugars
Gabija Poškaitė, David E. Wheatley, Neil Wells, Bruno Linclau & Davy Sinnaeve, 2023, Journal of Organic Chemistry, 88(19), 13908-13925
DOI: 10.1021/acs.joc.3c01503
Type: article
Reverse thiophosphorylase activity of a glycoside phosphorylase in the synthesis of an unnatural Manβ1,4GlcNAc library
2023, Chemical Science, 14(42), 11638-11646
DOI: 10.1039/d3sc04169g
Type: article
Synthesis and structural characteristics of all mono- and difluorinated 4,6-dideoxy-d-xylo-hexopyranoses
David Wheatley, Clement Q Fontenelle, Rama krishna K Kuppala, Robert Szpera, Edward L. Briggs, Jean B Vendeville, Neil J. Wells, Mark Light & Bruno Linclau, 2021, Journal of Organic Chemistry, 86(11), 7725–7756
DOI: 10.1021/acs.joc.1c00796
Type: article
Introducing affinity and selectivity into galectin-targeting nanoparticles with fluorinated glycan ligands
Sarah-Jane Richards, Tessa Keenan, Jean-Baptiste Vendeville, David Wheatley, Harriet Chidwick, Darshita Budhadev, Claire Council, Claire S. Webster, Helene Ledru, Alexander Baker, Marc Walker, M. Carmen Galan, Bruno Linclau, Martin A. Fascione & Matthew I. Gibson, 2020, Chemical Science, 12(3), 905-910
DOI: 10.1039/D0SC05360K
Type: article
Profiling substrate promiscuity of wild-type sugar kinases for multifluorinated monosaccharides
2020, Cell Chemical Biology, 27(9), 1199-1206.e5
DOI: 10.1016/j.chembiol.2020.06.005
Type: article