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Research group

Chemical Biology, Diagnostics and Therapeutics

We contribute to the progress of new developments in healthcare, the environment, bioenergy systems and bio-nanotechnology.

Part of Chemistry

About

Our group's research across both chemistry and biology means we are multidisciplinary by nature. We investigate the properties of a wide range of biomolecules, including DNA, proteins, lipids and carbohydrates. These can range from small synthetic models to biologically-derived macromolecular (large molecule) complexes. 

We regularly work in collaboration within the University of Southampton, with other institutions or with industrial partners.

Our current research projects include:

  • enzyme catalysis
  • protein-protein interactions
  • post-translational modifications
  • lipidomics

People, projects and publications

People

Professor Martin Feelisch

Prof of Exp Med & Int Biol

Research interests

  • Role of Nutrition and Exercise in Health & Resilience
  • Origin-of-Life Chemistry and Evolution
  • Stress Signaling & Redox Regulation

Accepting applications from PhD students

Dr Matthias Baud

Associate Professor

Research interests

  • Chemical Biology
  • Medicinal Chemistry
  • Protein Sciences

Accepting applications from PhD students

Dr Niall Hanrahan

Research Fellow

Dr Sam Thompson

Associate Professor

Research interests

  • Chemical Biology
  • Organic Synthesis
  • Medicinal Chemistry

Accepting applications from PhD students

Dr Seung Lee

Associate Professor

Research interests

  • Chemical biology
  • Antimicrobial resistance
  • Glycan processing enzymes

Dr Simon Lane

Research Fellow

Professor Sumeet Mahajan MSc, MTech, PhD, FHEA, FRSC

Prof of Molecular BioPhotonics & Imaging

Research interests

  • New chemical biology methods based on Raman spectroscopy and label-free imaging
  • Methodology and device development for commercialisation and clinical translation
  • Neuro-diagnostics and early detection of dementia and neurodegenerative diseases

Accepting applications from PhD students

Ms Tina-Thien Ho

Marie Sklodowska-Curie Fellow ITN

Dr Ysobel Baker

Royal Society University Research Fellow

Research interests

  • DNA chemistry
  • Nucleic acid chemistry
  • Nucleic acid therapeutics

Accepting applications from PhD students

We research the development of chemistry-driven approaches to modulate proteins’ physiological activity in a wide sense, with the ultimate goal to deliver new tools to study proteins’ function in living systems.
Associate Professor